林燕;刘华绪;

• 1:中国中西医结合学会皮肤性病学专业委员会皮肤影像学组
• 2:国家远程医疗与互联网医学中心皮肤科专委会
• 3:国家皮肤与免疫疾病临床医学研究中心
• 4:华夏皮肤影像人工智能协作组

摘要(Abstract)：

<正>反射式共聚焦显微镜(reflectance confocal micro scopy,RCM)是基于光学共聚焦原理的皮肤在体扫描装置,可在细胞水平上对皮肤进行无创、实时、动态成像,其分辨率近似于组织学病理。RCM在皮肤科应用广泛,是目前常用的皮肤影像学诊断技术,最初主要用于肿瘤性皮肤病的早期辅助诊断,现广泛应用于炎症性皮肤病、色素异常性皮肤病等

关键词(KeyWords)：

Abstract:

Keywords:

基金项目(Foundation): 国家重点研发计划重大科学仪器设备开发专项(2016YFF0101606)

作者(Authors): 林燕;刘华绪;

参考文献(References)：

• [1]Rajadhyaksha M,Grossman M,Esterowitz D,et al.In vivo confocal scanning laser microscopy of human skin:melanin provides strong contrast[J].J Invest Dermatol,1995,104(6):946-952.
• [2]Li W,Wang S,Xu AE.Role of in vivo reflectance confocal microscopy in determining stability in vitiligo:a preliminary study[J].Indian J Dermatol,2013,58(6):429-432.
• [3]Hu SW,Bigby M.Pityriasis versicolor:a systematic review of interventions[J].Arch Dermatol,2010,146(10):1132-1140.
• [4]Lee HS,Chun YS,Hann SK.Nevus depigmentosus:clinical features and histopathologic characteristics in 67 patients[J].JAm Acad Dermatol,1999,40(1):21-26.
• [5]Pan ZY,Yan F,Zhang ZH,et al.In vivo reflectance confocal microscopy for the differential diagnosis between vitiligo and nevus depigmentosus[J].Int J Dermatol,2011,50(6):740-745.
• [6]Lai LG,Xu AE.In vivo reflectance confocal microscopy imaging of vitiligo,nevus depigmentosus and nevus anem icus[J].Skin Res Technol,2011,17(4):404-410.
• [7]Kim SK,Kim EH,Kang HY,et al.Comprehensive understanding of idiopathic guttate hypomelanosis:clinical and histopathological correlation[J].Int J Dermatol,2010,49(2):162-166.
• [8]Montero LC,Belinchón I,Toledo F,et al.Progressive macular hypomelanosis,excellent response with narrow-band ultraviolet B phototherapy[J].Photodermatol Photoimmunol Photomed,2011,27(3):162-163.
• [9]Jadotte YT,Janniger CK.Pityriasis alba revisited:perspectives on an enigmatic disorder of childhood[J].Cutis,2011,87(2):66-72.
• [10]Vinod S,Singh G,Dash K,et al.Clinico epidemiological study of pityriasis alba[J].Indian J Dermatol Venereol Leprol,2002,68(6):338-340.
• [11]Liu H,Lin Y,Nie X,et al.Histological classification of melasma with reflectance confocal microscopy:a pilot study in Chinese patients[J].Skin Res Technol,2011,17(4):398-403.
• [12]Kang HY,Bahadoran P,Suzuki I,et al.In vivo reflectance con focal microscopy detects pigmentary changes in melasma at a cellular level resolution[J].Exp Dermatol,2010,19(8):e228-e233.