娜丽;马臻;赵文江;

• 1:内蒙古医科大学附属医院感染科

摘要(Abstract)：

目的探讨艾滋病患者CD4+T细胞水平与机会性感染和病毒载量的相关性。方法选取本院2016年1月至2017年1月收治的128例艾滋病患者为研究对象,测定其血清中的CD4+T细胞水平和病毒载量,随访6个月,统计发生机会性感染的患者例数和类型,分析CD4+T细胞与机会性感染和病毒载量的相关性。结果 68例患者于6个月内发生机会性感染,感染率为53.12%。最常见的感染类型为细菌性肺炎(30.88%)、肺孢子菌肺炎(22.06%)和口腔念珠菌感染(16.18%)。发生机会性感染或病毒载量≥104/ml的患者CD4+T细胞水平均显著低于未发生机会性感染或病毒载量<104/ml的患者(均P <0.001)。多因素Logistic回归分析显示CD4+T细胞<100个/μl和病毒载量≥104/ml均是艾滋病患者发生机会性感染的危险因素(均P <0.05)。结论CD4+T细胞水平降低可增加艾滋病患者发生机会性感染的危险,应对其进行常规检测,避免机会性感染的发生。

关键词(KeyWords)： 艾滋病;CD4~+T细胞;机会性感染;病毒载量

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 娜丽;马臻;赵文江;

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