傅彩红;徐新;鲍莹;

• 1:南京医科大学附属儿童医院血液肿瘤科
• 2:南京医科大学附属儿童医院内科

摘要(Abstract)：

目的分析关节功能状态对血友病患儿生存质量的影响,探究改善患儿生存质量的方法。方法选取本院2013年5月至2018年5月收治的94例血友病患儿为研究对象,使用中文版血友病关节健康评估表2.1(haemophilia joint health score 2.1,HJHS 2.1)评估其关节功能状态,使用中文版儿童生活质量测定量表4.0版(pediatric quality of life inventory version 4.0,Peds QL 4.0)、血友病功能独立性评分(functional independence score in haemophilia,FISH)评估其生存质量。采用Pearson相关性分析探讨血友病患儿HJHS 2.1评分与PedsQL 4.0评分、FISH的相关性,分析关节功能状态对患儿生存质量的影响。结果 94例患儿平均HJHS 2.1评分为(19.55±2.30)分,平均PedsQL 4.0评分为(1.82±0.63)分,平均FISH为(25.26±5.17)分。Pearson相关性分析示,PedsQL 4.0评分总分及各功能项评分与HJHS 2.1评分总分及各项目评分均呈正相关(P_均<0.05),FISH总分与HJHS 2.1评分总分及各项目评分均呈负相关(P_均<0.05)。结论血友病患儿关节功能状态普遍较差,随着患儿关节功能的恶化,其生活质量、日常生活活动能力明显下降,是影响患儿生存质量的重要原因,应考虑早期干预。

关键词(KeyWords)： 关节功能;血友病;生存质量;日常生活活动能力

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 傅彩红;徐新;鲍莹;

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