支气管哮喘全球倡议(2012更新版)简介
杨慧,向平超
摘要(Abstract):
<正>支气管哮喘全球倡议(The Global Initiative for Asthma,GINA)指南(以下简称"2012版指南")始建于1993年,是基于当时最好的科学数据给出的哮喘管理推荐。它的第一个报告:全球哮喘管理和预防策略发表于1995年,并分别于2002年、2006年基于当时发表的研究进行了修订。2002年建立GINA科学委员会,委员们汇集并评估哮喘相关文献,以便进行更新。自2006年开始,每年12月份对GINA进行一次更新,即结合上一年7月1
关键词(KeyWords):
基金项目(Foundation):
作者(Author): 杨慧,向平超
参考文献(References):
- [1]Global strategy for asthma management and prevention updated2012[EB/OL].http://www.ginasthma.org.
- [2]Burke H,Leonardi-Bee J,Hashim A,et al.McKeever TM.Prenatal and passive smoke exposure and incidence of asthma and wheeze:systematic review and meta-analysis[J].Pediatrics,2012,129(4):735-744.
- [3]Kerstjens HA,Disse B,Schroder-Babo W,et al.Tiotropium improves lung function in patients with severe uncontrolled asthma:a randomized controlled trial[J].J Allergy Clin lmmunol,2011,128(2):308-314.
- [4]Bateman ED,Kornmann O,Schmidt P,et al.Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-Arg/Arg patients with asthma[J].J Allergy Clin lmmunol,2011,128(2):315-322.
- [5]Molfino NA,Slutsky AS,Julià-SerdàG,et al.Assessment of airway tone in asthma.Comparison between double lung transplant patients and healthy subjects[J].Am Rev Respir Dis,1993,148(5):1238-1243.
- [6]Kanazawa H,Kawaguchi T,Shoji S,et al.Synergistic effect of nitric oxide and vasoactive intestinal peptide on bronchoprotection against histamine in anesthetized guinea pigs[J].Am J Respir Crit Care Med,1997,155(2):747-750.
- [7]Wessler IK,Kirkpatrick CJ.The non-neuronal cholinergic system:an emerging drug target in the airways[J].Pulm Pharmacol Ther,2001,14(6):423-434.
- [8]Profita M,Giorgi RD,Sala A,et al.Muscarinic receptors,leukotriene B4 production and neutrophilic inflammation in COPD patients[J].Allergy,2005,60(11):1361-1369.
- [9]Hagforsen E,Einarsson A,Aronsson F,et al.The distribution of choline acetyltransferase-and acetylcholinesteraselike immunoreactivity in the palmar skin of patients with palmoplantar pustulosis[J].Br J Dermatol,2000,142(2):234-242.
- [10]Fujii T,Kawashima K.An independent non-neuronal cholinergic system in lymphocytes[J].Jpn J Pharmacol,2001,85(1):11-15.
- [11]Wessler I,Kilbinger H,Bittinger F,et al.The non-neuronal cholinergic system in humans:expression,function and pathophysiology[J].Life Sci,2003,72(18-19):2055-2061.
- [12]Newnham DM,McDevitt DG,Lipworth BJ.Bronchodilator subsensitivity after chronic dosing with eformaterol in patients with asthma[J].Am J Med,1994,97(1):29-37.
- [13]Nelson HS,Weiss ST,Bleecker ER,et al.The Salmeterol Multicenter Asthma Research Trial:a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol[J].Chest,2006,129(1):15-26.
- [14]Kemp J,Armstrong L,Wan Y,et al.Safety of formoterol in adults and children with asthma:a meta-analysis[J].Ann Allergy Asthma lmmunol,,2011,107(1):71-78.
- [15]Bateman E,nelson H,Bousquet J,et al.Meta-analysis:effects of adding salmeterol to inhaled corticosteroids on serious asthma-related events[J].Ann Intern Med,2008,149(1):33-42.
- [16]Sears MR,Radner F.Safety of formoterol in asthma clinical trials:an update[J].Eur Respir J,2013.[Epub ahead of print].
- [17]Mansur AH,Kaiser K.Long-term safety and efficacy of luticasone/formoterol combination therapy in asthma[J].J Aerosol Med Pulm Drug Deliv,2013,26(4):190-199.
- [18]Nathan RA,D'Urzo A,Blazhko V,et al.Safety and efficacy offluticasone/formoterol combination therapy inadolescent and adult patients with mild-to-moderate asthma:a randomised controlled trial[J].BMC Pulm Med.2012,12:67.
- [19]Humbert M,Beasley R,Ayres J,et al.Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy(GINA 2002 step 4 treatment):INNOVATE[J].Allergy,2005,60(3):309-316.
- [20]Hanania NA,Alpan O,Hamilos DL,et al.Omalizumab in severe allergic asthma inadequately controlled with standard therapy:a randomized trial[J].Ann Internal Med,2011,154(9):573-582.
- [21]Ozgür ES,Ozge C,Ilvan A,et al.Assessment of long-term omalizumab treatment in patients with severe allergic asthma long-term omalizumab treatment in severe asthma[J].J Asthma,2013,50(6):687-694.
- [22]Garcia G,Magnan A,Chiron R,et al.A Proof-of-concept,randomized,controlled trial of omalizumab in patients with severe,difficult-to-control,nonatopic asthma[J].Chest,2013,144(2):411-419.
- [23]Zeiger RS,Mauger D,Bacharier LB,et al.CARE Network of the national Heart,Lung,and Blood Institute.Daily or intermittent budesonide in preschool children with recurrent wheezing[J].N Engl J Med,2011,365(21):1990-2001.
- [24]Shah S,Sawyer SM,Toelle BG,et al.Improving paediatric asthma outcomes in primariy health care:a randomized controlled trial[J].Med J Aust,2011,195(7):405-409.
- [25]Bousquet J,Yssel H,Vignola AM.Is allergic asthma associated with delayed fetal maturation or the persistence of conserved fetal genes?[J].Allergy.2000,55(12):1194-1197.
- [26]Jones CA,Holloway JA,Warner JO.Does atopic disease start in foetal life?[J].Allergy,2000,55(1):2-10.
- [27]Gehring U,de Jongste JC,Kerkhof M,et al.The 8-year followup of the PIAMA intervention study assessing the effect of mite-impermeable mattress covers[J].Allergy,2012,67(2):248-256.
- [28]Beuther DA,Sutherland ER.Overweight,obesity,and incident asthma:a meta-analysis of prospective epidemiologic studies[J].Am J Respir Crit Care Med,2007,175(7):661-666.
- [29]Brashier B,Salvi S.Obesity and asthma:physiological perspective[J].J Allergy(Cairo),2013,2013:198068.
- [30]Stenius-Aarniala B,Poussa T,Kvarnstrom J,et al.Immediate and long term effects of weight reduction in obese people with asthma:randomized controlled study[J].BMJ,2000,320(7238):827-832.
- [31]Gamble J,Stevenson M,Heaney LG.A study of a multilevel intervention to improve non-adherence in difficult to control asthma[J].Respir Med,2011,105(9):1308-1315.
- [32]Castro M,Rubin AS,Laviolette M,et al.AIR2 Trial Study Group.Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma:a multicenter,randomized,double-blind,sham-controlled clinical trial[J].Am J Respir Crit Care Med,2010,181(2):116-124.
- [33]Thomson NC,Rubin AS,Niven RM,et al.AIR Trial Study Group.Long-term(5 year)safety of bronchial thermoplasty:Asthma Intervention Research(AIR)trial[J].BMC Pulm Med,2011,11:8.
- [34]James A,Mauad T,Abramson M,et al.Airway smooth muscle hypertrophy and hyperplasia in asthma[J].Am J Respir Crit Care Med,2012,186(6):568.
- [35]Miller JD,Cox G,Vincic L,et al.A prospective feasibility study of bronchial thermoplasty in the human airway[J].Chest,2005,127(6):1999-2006.
- [36]Castro M,Rubin A,Laviolette M,et al.AIR2 Trial Study Group.Persistence of effectiveness of bronchial thermoplasty in patients with severe asthma[J].Ann Allergy Asthma Immunol,2011,107(1):65-70.
- [37]Perrin K,Wijesinghe M,Healy B,et al.Randomised controlled trial of high concentration versus titrated oxygen therapy in severe exacerbations of asthma[J].Thorax,2011,66(11):937-941.
- [38]De Groene GJ,Pal TM,Beach J,et al.Workplace interventions for treatment of occupational asthma[J].Cochrane Database Syst Rev,2011,(5):CD006308.
- [39]Lin FJ,Dimich-Ward H,Chan-Yeung M.Longitudinal decline in lung function in patients with occupational asthma due to western red cedar[J].Occup Environ Med,1996,53(11):753-756.
- [40]Fishwick D,Barber CM,Bradshaw LM,et al.Standards of care for occupational asthma:an update[J].Thorax,2012,67(3):278-280.
- [41]Kiliander TO,Harding SM,Field SK,et al.Effects of esomeprazole 40 mg twice daily on asthma:a randomized placebo-controlled trial[J].Am J Respir Crit Care Med,2006,173(10):1091-1097.
- [42]Chan WWW,Chiou E,Obstein KL,et al.The efficacy of pump inhibitors for the treatment of asthma in adults:a metaanalysis[J].Arch Intern Med,2011,171(7):620-629.
- [43]Holbrook JT,Wise RA,Gold BD,et al.Writing Committee for the American Lung Association Asthma Clinical Reseach Centers.Lansoprazole for children with poorly controlled asthma:a randomized controlled trial[J].JAMA,2012,307(4):373-381.