心肌细胞超微结构改变与心力衰竭
戚艳超,徐明
摘要(Abstract)：
心肌细胞是心脏收缩和舒张的基本结构单元,由肌膜/横管、肌质网、肌纤维、线粒体、细胞核等多种细胞器构成。心肌细胞及其亚细胞结构是维持心脏正常工作的结构基础。在多种原因所致的心脏重塑发生时,这些结构出现了一系列的改变,导致心脏舒缩功能紊乱,并进一步加重重塑,最终导致心力衰竭的发生。因此,了解心肌细胞及其亚细胞结构在心力衰竭发展过程中的变化及其调控机制对心力衰竭的早期诊断和治疗具有重要的意义。本文将就此作一简要综述。
关键词(KeyWords)： 心肌细胞超微结构;心力衰竭
基金项目(Foundation): 国家自然科学基金项目(81070196);; 教育部新世纪优秀人才项目(BMU20100012)
作者(Author): 戚艳超,徐明
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