动脉粥样硬化斑块无创性超声检测方法
张梅
摘要(Abstract)：
<正>动脉粥样硬化易损斑块破裂和血栓形成是急性冠状动脉综合征(acute coronary syndrome,ACS)的主要发病机制。易损斑块是指易于形成血栓或可能迅速进展为罪犯病变的斑块。随着近年来动脉粥样硬化治疗的新观点重新强调动脉粥样硬化是一种全身性疾病,早期诊断和治疗对于防治心血管病事件具有重要的意义。无创高频超声检查和分析动脉粥样硬化斑块的方法显示出其诊断的优越性。
关键词(KeyWords)：
基金项目(Foundation): 国家重点基础研究发展计划(973重大课题子课题,2010CB732605)
作者(Author): 张梅
参考文献(References)：
- [1]张梅,张运,高月花,等.超声检查对颈动脉粥样硬化血管重构的研究[J].中华超声影像学杂志,2002,11(4):229-231.
- [2]Bauer M,Caviezel S,Teynor A,et al.Carotid intima-media thickness as a biomarker of subclinical atherosclerosis[J].Swiss Med Wkly,2012,25,142:w13705.
- [3]Van den Oord SC,Sijbrands EJ,Ten Kate GL,et al.Carotid intima-media thickness for cardiovascular risk assessment:systematic review and meta-analysis[J].Atherosclerosis,2013.
- [4]Lorenz MW,Markus HS,Bots ML,et al.Prediction of clinicalcardiovascular events with carotid intima-media thickness:a systematic review and meta-analysis[J].Circulation,2007,115(4):459-467.
- [5]Stein JH,Korcarz CE,Hurst RT,et al.Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk:aconsensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness TaskForce.Endorsed by the Society for Vascular Medicine[J].J Am Soc Echocardiogr,2008,21(2):93-111.
- [6]Sillesen H,Fuster V.Predicting coronary heart disease:from Framingham Risk Score to ultrasound bioimaging[J].Mt Sinai J Med,2012,79(6):654-663.
- [7]Saba L,Sanfilippo R,Sannia S.Association between carotid artery plaque volume,composition,and ulceration:a retrospective assessment with MDCT[J].AJR Am J Roentgenol,2012,199(1):151-156.
- [8]王志蕴,张梅,刘晓玲,等.速度向量成像技术早期无创性评价动脉硬化的临床研究[J].中华医学超声杂志(电子版),2009,6(2):252-258.
- [9]Zhang L,Liu Y,Zhang PF,et al.Peak radial and circumferential strain measured by velocity vector imaging is a novel index for detecting vulnerable plaques in a rabbit model of atherosclerosis[J].Atherosclerosis,2009,211(1):146-152.
- [10]Zhang PF,Su HJ,Yao GH,et al.Plaque volume compression ratio,a novel biomechanical index,is independently associated with ischemic cerebrovascular events[J].J Hypertens,2009,27(2):348-356.
- [11]Kim KH,Park JC,Yoon HJ,et al.Usefulness of aortic strain analysis by velocity vector imaging as a new echocardiographic measure of arterial stiffness[J].J Am Soc Echocardiogr,2009,22(12):1382-1388.