1型糖尿病残存胰岛功能保护——免疫治疗
郑帅,顾愹,杨涛
摘要(Abstract):
<正>1型糖尿病(type 1 diabetes mellitus,T1DM)是一种慢性自身免疫性疾病,抗原特异性、致病性T细胞攻击胰岛导致分泌胰岛素的β细胞特异性破坏,引起临床高血糖症状。典型的T1DM在患者出现临床症状时已丧失大部分胰岛,仅有15%~20%的β细胞存活[1]。从自身免疫性糖尿病的自然病程来看,β细胞的自身免疫性破坏在高
关键词(KeyWords):
基金项目(Foundation): 国家自然科学基金(30971405,81270897)
作者(Author): 郑帅,顾愹,杨涛
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