戴皓,杨涛

• 1:南京医科大学第一附属医院内分泌科

摘要(Abstract)：

<正>2013年以来糖尿病的降糖方案成为国内外糖尿病专家讨论的话题,且降糖治疗的目标值也成为人们关注的焦点,加拿大糖尿病协会(Canadian Diabetes Association,CDA)更新并颁布了2013版糖尿病预防和管理指南(以下简称"2013版指南"),2013版指南在原有指南的基础上,基于近年来的

关键词(KeyWords)：

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 戴皓,杨涛

参考文献(References)：

• [1]American Diabetes Association.Diagnosis and classification of diabetes mellitus[J].Diabetes care,2012,35(suppl1):S64-S71
• [2]Heianza Y,Arase Y,Fujihara K,et al.Screening for pre-diabetes to predict future diabetes using various cut-off points for HbA(1c)and impaired fasting glucose:the Toranomon Hospital Health Management Center Study4(TOPICS4)[J].Diabetic Med.2012,29(9):e279-285.
• [3]Bingley PJ.Interactions of age,islet cell antibodies,insulin autoantibodies,and first-phase insulin response in predicting risk of progression to IDDM in ICA relatives:the ICARUS data set.Islet Cell Antibody Register Users Study[J].Diabetes,1996,45(12):1720-1728.
• [4]Cowie CC,Rust KF,Byrd-Holt DD,et al.Prevalence of diabetes and impaired fasting glucose in adults in the U.S.population:National Health And Nutrition Examination Survey1999-2002[J].Diabetes Care,2006,29(6):1263-1268.
• [5]Simmons RK,Rahman M,Jakes RW,et al.Effect of population screening for type2diabetes on mortality:long term follow-up of the Ely cohort[J].Diabetologia,2011,54(2):312-319.
• [6]Nathan DM,Cleary PA,Backlund JY,et al.Intensive diabetes treatment and cardiovascular disease in patients with type1diabetes[J].N Engl J Med,2005,353(25):2643-2653.
• [7]DeWitt DE,Hirsch IB.Outpatient insulin therapy in type1and type2diabetes mellitus:scientific review[J].JAMA,2003,289(17):2254-2264.
• [8]Schernthaner G,Wein W,Shnawa N,et al.Preprandial vs.post-prandial insulin lispro:a comparative crossover trial in patients with type1diabetes[J].Diabet Med,2004,21(3):279-284.
• [9]Jovanovic L,Giammattei J,Acquistapace M,et al.Efficacy comparison between preprandial and postprandial insulin aspart administration with dose adjust-ment for unpredictable meal size[J].Clin Ther,2004,26(9):1492-1497.
• [10]Warren E,Weatherley-Jones E,Chilcott J,et al.Systematic review and economic evaluation of a long-acting insulin analogue,insulin glargine[J].Health Technol Assess,2004,8(45):1-57.
• [11]Bolli GB.How to ameliorate the problem of hypoglycemia in intensive as well as nonintensive treatment of type1diabetes[J].Diabetes Care,1999,22(suppl2):B43-B52.
• [12]Monnier L,Lapinski H,Colette C.Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type2diabetic patients:variations with increasing levels of HbA(1c)[J].Diabetes Care,2003,26(3):881-885.
• [13]United Kingdom Prospective Diabetes Study Group.United Kingdom Prospective Diabetes Study24:a6-year,randomized,controlled trial comparing sulfonylurea,insulin,and metformin therapy in patients with newly diagnosed type2diabetes that could not be controlled with diet therapy[J].Ann Intern Med,1998,128(3):165-175.
• [14]Sumeet R,Singh SR,Ahmad F,et al.Efficacy and safety of insulin analogues for the management of diabetes mellitus:a meta-analysis[J].CMAJ,2009,180(4):85-97.
• [15]Weng J,Li Y,Xu W,et al.Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type2diabetes:a multicentre randomised parallel-group trial[J].Lancet,2008,371(9626):1753-1760.
• [16]Ryan EA,Imes S,Wallace C.Short-term intensive insulin therapy in newly diagnosed type2diabetes[J].Diabetes Care,2004,27(5):1028-1032.
• [17]Coppelli A,Giannarelli R,Vistoli F,et al.The beneficialeffects of pancreas transplant alone on diabetic nephropathy[J].Diabetes Care,2005,28(6):1366-1370.
• [18]Sureshkumar KK,Patel BM,Markatos A,et al.Quality of life after organ transplantation in type1diabetics with end-stage renal disease[J].Clin Trans-plant,2006,20(1):19-25.
• [19]Robertson RP.Islet transplantation as a treatment for diabetes:a work in progress[J].N Engl J Med,2004,350(7):694-705.
• [20]Barker JM.Clinical review:type1diabetes-associated autoimmunity:natural history,genetic associations,and screening[J].J Clin Endocrinol Metab,2006,91(4):1210-1217.
• [21]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2010年版)[J].中国医学前沿杂志(电子版),2011,3(6):54-104.