心肌肥厚的研究进展
熊肇军,董吁钢
摘要(Abstract):
<正>心肌肥厚是高血压等患者心脑血管事件的独立危险因素。多种刺激如压力过负荷、神经体液因子以及心肌收缩蛋白基因突变等导致心肌细胞出现许多组织细胞形态学的适应性反应。肥大特征一般表现为:①心肌细胞体积增大;②蛋白质合成增加;③"胚胎期"基因再表达。大多数初期的心肌肥厚有代偿意义,持续性心肌肥厚最终可致扩张性心肌病、心力衰竭和猝死。心肌肥厚的分子机制非常复
关键词(KeyWords):
基金项目(Foundation):
作者(Author): 熊肇军,董吁钢
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