马欣昕,苏闻,陈海波

• 1:北京医院神经内科

摘要(Abstract)：

<正>帕金森病(Parkinson's disease,PD)是一种常见于中老年人的神经变性疾病,迄今为止,其诊断和药物疗效评价主要依赖于临床,缺少客观证据,虽然正电子发射计算机断层显像(PET)和单光子发射计算机化断层显像(SPECT)能提示PD患者黑质及基底节神经核团功能的异常,但对于结构改变的显示及其对早期诊断的提示意义不尽如人意,且具有一定的放射性危害,临床应用较为局限。随着磁共振成像(MRI)技术的不断发展,越来越多的研究者试图通过该手段,筛选适合PD早期诊断的生物标记物及其相关检测方法,为PD的早期诊

关键词(KeyWords)：

Abstract:

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基金项目(Foundation): 国家科技支撑项目(2012BAI10B03)

作者(Author): 马欣昕,苏闻,陈海波

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