肺移植术后的原发性移植物功能丧失的诊治进展Progress in diagnosis and treatment of primary graft dysfunction after lung transplantation
崔力元;陈军;
摘要(Abstract):
肺移植是良性终末期肺疾病唯一有效的治疗方式。随着供者肺组织保存方法和手术技术水平的不断提高,肺移植手术得以广泛开展,目前该技术已趋于成熟。然而,由于肺独特的解剖结构和生理功能,导致肺部手术围术期并发症较为复杂,如何控制术后并发症、改善肺移植受者预后、延长患者术后生存期等问题逐渐成为研究的焦点,原发性移植物功能丧失(primary graft dysfunction,PGD)是肺移植术后早期发生率较高的一种并发症,也是威胁肺移植受者生存的重要因素。本文将对肺移植术后PGD发生机制、危险因素、诊断、预防及治疗等进行系统综述。
关键词(KeyWords): 肺移植;原发性移植物功能丧失;危险因素;治疗;预防
基金项目(Foundation): 国家自然科学基金(81773207);; 天津市自然科学基金重点项目(16JCZDJC34200)
作者(Authors): 崔力元;陈军;
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