反流性食管炎和胃食管阀瓣分级的相关性及其危险因素分析Analysis of correlation between RE and GVEF and its risk factors
柯冀;伍冀湘;李建业;于磊;
摘要(Abstract)：
目的研究反流性食管炎(reflux esophagitis,RE)与胃食管阀瓣(gastroesophageal flap valve,GEFV)分级的相关性,分析RE发生的危险因素。方法选取2015年1月至2016年12月本院接诊的302例RE患者为研究对象,根据胃镜影像对患者GEFV进行分级。分析GEFV分级与RE分级的相关性、RE患者GEFV分级与治疗方案的关系,并分析RE发生的危险因素。结果随着GEFV分级的增加,RE分级也随之增加,两者呈正相关(r=0.126,P <0.05);随着GEFV分级的增加,接受手术治疗的患者例数亦增加,两者之间呈正相关(r=0.455,P <0.001);预后良好组患者和预后不良组患者的年龄、性别、RE家族史、高血压病史、饮酒史、高脂血症病史、GEFV分级比较差异均具有显著性(P_均<0.05),两组患者住院天数比较无显著差异(P> 0.05);Logistic回归分析显示:年龄、性别、RE家族史、高血压病史、糖尿病病史、饮酒、高脂血症病史、GEFV分级为影响RE发生的危险因素。结论 GEFV分级判断RE患者病情严重程度具有一定的应用价值,接受手术治疗的RE患者随着GEFV分级的增加而增加。
关键词(KeyWords)： 反流性食管炎;胃食管阀瓣;相关性;危险因素
基金项目(Foundation):
作者(Authors): 柯冀;伍冀湘;李建业;于磊;
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