快速眼球运动睡眠行为障碍与神经系统变性疾病
沈赟,刘春风
摘要(Abstract):
快速眼球运动睡眠行为障碍(REM sleep behavior disorder,RBD)是一种并非罕见的异态睡眠,分为原发性和继发性。目前较多的研究认为约40%~65%的原发性RBD将发展成为神经系统变性疾病,主要为α-突触核蛋白疾病(包括帕金森病、路易体痴呆及多系统萎缩)。原发性RBD与神经系统变性疾病的一些早期临床特征存在重叠。RBD为疾病早期诊断和神经保护治疗提供了帮助。
关键词(KeyWords): 快速眼球运动睡眠行为障碍;帕金森病;路易体痴呆;多系统萎缩
基金项目(Foundation): 江苏省医学领军人才与创新团队及苏州市医学重点学科专项经费资助;; 苏州市科技发展计划(SZS201205)
作者(Author): 沈赟,刘春风
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